Optimal powder flow is essential in almost all pharmaceutical processes. Not only in unit operations involved in the production of solid dosage forms such as tableting, capsule filling and roll compaction, but also for processes used to produce liquid or semi-solid preparations. Poor flow can lead to processing problems, e.g. inconsistent feeding, air entrainment, but more importantly also to rejections due to compromised dosage uniformity. Active Pharmaceutical Ingredients (APIs) in particular often exhibit poor flowability. Multiple factors contribute to poor powder, many of which have been identified and described in detail. Particle size and particle size distribution (PSD) for example have a major influence on flowability but particle shape and other factors such as electrostatic charge can have a significant impact. Batch processing has traditionally dominated pharmaceutical production but in recent years, continuous manufacturing has grown in popularity due to the benefits it can deliver, e.g. improved and accelerated scale-up, enhanced process understanding and in particular real-time quality control. Monitoring raw material and product flow using in-line tools enables to process parameters to be adjusted real-time in response to any deviations detected. However, new technologies often come with new challenges. In continuous manufacturing, powder flow becomes even more critical if high product quality and a stable manufacturing process are to be maintained. Glidants, such as colloidal silicon dioxide, are often used to enhance flowability and can offer an efficient and economical alternative to granulation. However, use of this material in a continuous process can be challenging due to its low bulk density and poor feeding capability. The webinar will provide an introduction to glidant materials and how their impact on flowability of blends has been successfully evaluated using the FT4 Powder Rheometer. Speaker - Marek Lachmann | Business Development Manager | Chemische Fabrik Budenheim KG

麦克仪器公司是提供材料表征解决方案的全球领导厂商，在密度、比表面积及孔隙度、粒度及粒形、粉体表征、催化剂表征及工艺开发等五个核心领域拥有仪器和应用技术。

麦克仪器公司成立于1962年，总部位于美国佐治亚州诺克罗斯，在全球拥有400多名员工。公司同时具备丰富的科学知识库和内部生产制造，为石油加工、石化产品和催化剂、食品和制药等多个行业，以及下一代材料例如石墨烯、MOF材料、纳米催化剂和沸石等表征提供高性能产品。公司设有Particle Testing Authority（PTA）实验室,可提供商业测试服务。

战略收购富瑞曼科技有限公司（Freeman Technology Ltd）和PID公司(PID Eng & Tech)，也反映公司一直致力于在粉体和催化等工业关键领域提供优化、集成的解决方案。